Dr. Jacqueline Miller Holt is a legally qualified, registered toxicologist and senior scientific and regulatory affairs leader with extensive experience translating complex science into business-relevant strategy, regulatory positions, and clear communications for scientific and non-scientific audiences. She currently serves as Vice President, Scientific and Regulatory Affairs at JTI in Geneva, where she provides strategic leadership across reduced-risk and combustible product-related scientific and regulatory matters.
With a multidisciplinary background spanning toxicology, biomedical sciences, and law, Dr. Miller Holt holds a PhD from the University of Bristol and an LL.B from BPP Law School London. She has been a UK and European Registered Toxicologist since 2003 and is also listed on the Swiss Register of Toxicologists since 2014.
Since joining JTI in 2005, Dr. Miller Holt has held progressively senior roles, including Scientific and Regulatory Affairs Toxicology Director, Science Engagement Director, and Vice President. Her work has included leading toxicology teams, developed product stewardship and tested strategies, supporting regulatory submissions and ingredient disclosures worldwide, and shaping company positions on scientific and product-related regulatory issues. She has also played a key role in advancing the use of current scientific approaches, including new approach methodologies, in silico methods, in vitro testing strategies, and analytical techniques to assess tobacco and nicotine-containing products.
Dr. Miller Holt is recognized for her ability to work across functions, disciplines, and organizational levels, building credible relationships with internal and external stakeholders and representing JTI in cross-industry scientific forums. She is an active contributor to the scientific literature, with publications in in vitro toxicology, dosimetry, new approach methodologies, and nicotine pouch products.